How to treat Gastric Ulcers

How to treat Gastric Ulcers


As acids are the important causative factors of ulcers current treatment targets the suppression of gastric acids creating an environment to allow ulcer healing. Our clinic has a range of gastric ulcer treatment, which includes oral and injectable mediation.

 ·   Omeprazole paste

o   Oral paste, once a day in mouth

§  Omeprazole suppresses gastric acid by specific inhibition of the H+/K+-ATPase system found at the secretory surface of gastric parietal cells

§  It will block gastric acid secretion irrespective of the stimulus

§  Maximum acid suppression occurs after 3-5 days of treatment

·        Omeprazole injection

o   Intramuscular injection; 2 injections 2 weeks apart


·        Ranitidine 

o   Oral paste, once a day in mouth

§  Decreases acid secretion by inhibiting histamine2 receptors on gastric parietal cells


·        Sucralfate oral powder

o   Acts as an effective barrier to the stomach lining to prevent penetration of acid, pepsin, and bile salts

How to Manage Horses with Gastric Ulcers

  • Avoid long periods without food by feeding frequent small meals throughout the day

  • Allow horses to a constant supply of hay

  • Place feed bins on the ground to simulate the horse’s normal grazing position as this helps the chewing action and stimulates salvia production which acts as a buffer to the stomach acid

  • Feed a small amount of fibre 20 minutes prior to work/exercise as it helps create physical barrier for the stomach lining

  • Avoid and/or teach your horse to deal with physical and behavioural stress

  • Avoid long treatments with non-steroidal anti-inflammatory drugs such as Phenylbutazone.

Zoe Meyer